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Pneumococcal IgA1 Protease Subverts Specific Protection By Human IgA1
Bacterial IgA1 proteases may sabotage the protective effects of IgA. In vitro, both exogenous and endogenously-produced IgA1 protease inhibited phagocytic killing of Streptococcus pneumoniae by capsule-specific IgA1 human monoclonal antibodies (hMAb's), but not IgA2. These IgA1 proteases cleave...
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| Pubblicato in: | Mucosal Immunol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4456019/ https://ncbi.nlm.nih.gov/pubmed/23820749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2013.41 |
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