Streptococcus pneumoniae IgA1 protease: A metalloprotease that can catalyze in a split manner in vitro

IgA1 proteases (IgA1P) from diverse pathogenic bacteria specifically cleave human immunoglobulin A1 (IgA1) at the hinge region, thereby thwarting protective host immune responses. Streptococcus pneumoniae (S. pneumoniae) IgA1P shares no sequence conservation with serine or cysteine types of IgA1Ps o...

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Bibliografske podrobnosti
izdano v:Protein Sci
Main Authors: Chi, Ying‐Chih, Rahkola, Jeremy T., Kendrick, Agnieszka A., Holliday, Michael J., Paukovich, Natasia, Roberts, Thomas S., Janoff, Edward N., Eisenmesser, Elan Z.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5326571/
https://ncbi.nlm.nih.gov/pubmed/28028839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3110
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