Streptococcus pneumoniae IgA1 protease: A metalloprotease that can catalyze in a split manner in vitro

IgA1 proteases (IgA1P) from diverse pathogenic bacteria specifically cleave human immunoglobulin A1 (IgA1) at the hinge region, thereby thwarting protective host immune responses. Streptococcus pneumoniae (S. pneumoniae) IgA1P shares no sequence conservation with serine or cysteine types of IgA1Ps o...

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Publicat a:Protein Sci
Autors principals: Chi, Ying‐Chih, Rahkola, Jeremy T., Kendrick, Agnieszka A., Holliday, Michael J., Paukovich, Natasia, Roberts, Thomas S., Janoff, Edward N., Eisenmesser, Elan Z.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5326571/
https://ncbi.nlm.nih.gov/pubmed/28028839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3110
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