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Antibody-enhanced pneumococcal adherence requires IgA1 protease

IgA, the major class of Ig in secretions, classically functions by interfering with microbial attachment to host tissues. Many mucosal pathogens, including Streptococcus pneumoniae, express an IgA1 protease that may circumvent the protective effects of this Ig subclass. Because these proteases are s...

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Detalhes bibliográficos
Main Authors: Weiser, Jeffrey N., Bae, Deborah, Fasching, Claudine, Scamurra, Ronald W., Ratner, Adam J., Janoff, Edward N.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153073/
https://ncbi.nlm.nih.gov/pubmed/12642661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0637469100
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