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Antibody-enhanced pneumococcal adherence requires IgA1 protease

IgA, the major class of Ig in secretions, classically functions by interfering with microbial attachment to host tissues. Many mucosal pathogens, including Streptococcus pneumoniae, express an IgA1 protease that may circumvent the protective effects of this Ig subclass. Because these proteases are s...

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Main Authors: Weiser, Jeffrey N., Bae, Deborah, Fasching, Claudine, Scamurra, Ronald W., Ratner, Adam J., Janoff, Edward N.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The National Academy of Sciences 2003
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC153073/
https://ncbi.nlm.nih.gov/pubmed/12642661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0637469100
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