Antibody-enhanced pneumococcal adherence requires IgA1 protease

IgA, the major class of Ig in secretions, classically functions by interfering with microbial attachment to host tissues. Many mucosal pathogens, including Streptococcus pneumoniae, express an IgA1 protease that may circumvent the protective effects of this Ig subclass. Because these proteases are s...

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Bibliografiska uppgifter
Huvudupphovsmän: Weiser, Jeffrey N., Bae, Deborah, Fasching, Claudine, Scamurra, Ronald W., Ratner, Adam J., Janoff, Edward N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2003
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC153073/
https://ncbi.nlm.nih.gov/pubmed/12642661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0637469100
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