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PINK1 and Parkin Control Localized Translation of Respiratory Chain Component mRNAs on Mitochondria Outer Membrane

Mitochondrion plays essential roles in many aspects of biology, and its dysfunction has been linked to diverse diseases. Central to mitochondrial function is oxidative phosphorylation (OXPHOS), accomplished by respiratory chain complexes (RCCs) encoded by nuclear and mitochondrial genomes. How RCC b...

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Bibliografische gegevens
Gepubliceerd in:Cell Metab
Hoofdauteurs: Gehrke, Stephan, Wu, Zhihao, Klinkenberg, Michael, Sun, Yaping, Auburger, Georg, Guo, Su, Lu, Bingwei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455944/
https://ncbi.nlm.nih.gov/pubmed/25565208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.12.007
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