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PINK1 and Parkin Control Localized Translation of Respiratory Chain Component mRNAs on Mitochondria Outer Membrane

Mitochondrion plays essential roles in many aspects of biology, and its dysfunction has been linked to diverse diseases. Central to mitochondrial function is oxidative phosphorylation (OXPHOS), accomplished by respiratory chain complexes (RCCs) encoded by nuclear and mitochondrial genomes. How RCC b...

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Publicado en:Cell Metab
Autores principales: Gehrke, Stephan, Wu, Zhihao, Klinkenberg, Michael, Sun, Yaping, Auburger, Georg, Guo, Su, Lu, Bingwei
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455944/
https://ncbi.nlm.nih.gov/pubmed/25565208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.12.007
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