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PINK1 and Parkin Control Localized Translation of Respiratory Chain Component mRNAs on Mitochondria Outer Membrane

Mitochondrion plays essential roles in many aspects of biology, and its dysfunction has been linked to diverse diseases. Central to mitochondrial function is oxidative phosphorylation (OXPHOS), accomplished by respiratory chain complexes (RCCs) encoded by nuclear and mitochondrial genomes. How RCC b...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Gehrke, Stephan, Wu, Zhihao, Klinkenberg, Michael, Sun, Yaping, Auburger, Georg, Guo, Su, Lu, Bingwei
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455944/
https://ncbi.nlm.nih.gov/pubmed/25565208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.12.007
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