Pin1 Inhibitor Juglone Exerts Anti-Oncogenic Effects on LNCaP and DU145 Cells despite the Patterns of Gene Regulation by Pin1 Differing between These Cell Lines

BACKGROUND: Prostate cancer initially develops in an androgen-dependent manner but, during its progression, transitions to being androgen-independent in the advanced stage. Pin1, one of the peptidyl-prolyl cis/trans isomerases, is reportedly overexpressed in prostate cancers and is considered to con...

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Vydáno v:PLoS One
Hlavní autoři: Kanaoka, Ryuhei, Kushiyama, Akifumi, Seno, Yasuyuki, Nakatsu, Yusuke, Matsunaga, Yasuka, Fukushima, Toshiaki, Tsuchiya, Yoshihiro, Sakoda, Hideyuki, Fujishiro, Midori, Yamamotoya, Takeshi, Kamata, Hideaki, Matsubara, Akio, Asano, Tomoichiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454534/
https://ncbi.nlm.nih.gov/pubmed/26039047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127467
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