Nalaganje...

The intrinsic apoptosis pathway mediates the pro-longevity response to mitochondrial ROS in C. elegans

The increased longevity of the C. elegans electron transport chain mutants isp-1 and nuo-6 is mediated by mitochondrial ROS (mtROS) signaling. Here we show that the mtROS signal is relayed by the conserved, mitochondria-associated, intrinsic apoptosis signaling pathway (CED-9/Bcl2, CED-4/Apaf1 and C...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell
Main Authors: Yee, Callista, Yang, Wen, Hekimi, Siegfried
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454526/
https://ncbi.nlm.nih.gov/pubmed/24813612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.02.055
Oznake: Označite
Brez oznak, prvi označite!