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Mitochondrial ROS and the Effectors of the Intrinsic Apoptotic Pathway in Aging Cells: The Discerning Killers!

It has become clear that mitochondrial reactive oxygen species (mtROS) are not simply villains and mitochondria the hapless targets of their attacks. Rather, it appears that mitochondrial dysfunction itself and the signaling function of mtROS can have positive effects on lifespan, helping to extend...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Hekimi, Siegfried, Wang, Ying, Noë, Alycia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021979/
https://ncbi.nlm.nih.gov/pubmed/27683586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00161
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