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Enhanced immunity in slowly aging mutant mice with high mitochondrial oxidative stress

The mitochondria of slowly aging Mclk1(+/−) mutant mice produce high levels of reactive oxygen species (ROS). These animals display enhanced immune reactivity in response to lipopolysaccharide, Salmonella, and tumor-cell grafts, experience limited damage from these treatments and are partially prote...

詳細記述

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書誌詳細
第一著者: Hekimi, Siegfried
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654596/
https://ncbi.nlm.nih.gov/pubmed/23734326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.23793
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