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Seneca Valley Virus 2C and 3C(pro) Induce Apoptosis via Mitochondrion-Mediated Intrinsic Pathway

Seneca Valley virus (SVV) is the only member of the genus Senecavirus of the Picornaviridae family. SVV can selectively infect and lyse tumor cells with neuroendocrine features and is used as an oncolytic virus for treating small-cell lung cancers. However, the detailed mechanism underlying SVV-medi...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Liu, Tingting, Li, Xiangmin, Wu, Mengge, Qin, Liuxing, Chen, Huanchun, Qian, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549803/
https://ncbi.nlm.nih.gov/pubmed/31191506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.01202
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