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A Mitochondrial Superoxide Signal Triggers Increased Longevity in Caenorhabditis elegans
The nuo-6 and isp-1 genes of C. elegans encode, respectively, subunits of complex I and III of the mitochondrial respiratory chain. Partial loss-of-function mutations in these genes decrease electron transport and greatly increase the longevity of C. elegans by a mechanism that is distinct from that...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2998438/ https://ncbi.nlm.nih.gov/pubmed/21151885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000556 |
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