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Lysosomal Signaling Molecules Regulate Longevity in Caenorhabditis elegans
Lysosomes are crucial cellular organelles for human health that function in digestion and recycling of extracellular and intracellular macromolecules. We describe a signaling role for lysosomes that affects aging. In the worm, Caenorhabditis elegans, the lysosomal acid lipase LIPL-4 triggered nuclea...
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| 出版年: | Science |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4425353/ https://ncbi.nlm.nih.gov/pubmed/25554789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1258857 |
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