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A 3D tension bioreactor platform to study the interplay between ECM stiffness and tumor phenotype

Extracellular matrix (ECM) structure, composition, and stiffness have profound effects on tissue development and pathologies such as cardiovascular disease and cancer. Accordingly, a variety of synthetic hydrogel systems have been designed to study the impact of ECM composition, density, mechanics,...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biotechnol
Autori principali: Cassereau, Luke, Miroshnikova, Yekaterina A., Ou, Guanqing, Lakins, Johnathon, Weaver, Valerie M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454500/
https://ncbi.nlm.nih.gov/pubmed/25435379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiotec.2014.11.008
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