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A 3D tension bioreactor platform to study the interplay between ECM stiffness and tumor phenotype

Extracellular matrix (ECM) structure, composition, and stiffness have profound effects on tissue development and pathologies such as cardiovascular disease and cancer. Accordingly, a variety of synthetic hydrogel systems have been designed to study the impact of ECM composition, density, mechanics,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biotechnol
Hauptverfasser: Cassereau, Luke, Miroshnikova, Yekaterina A., Ou, Guanqing, Lakins, Johnathon, Weaver, Valerie M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454500/
https://ncbi.nlm.nih.gov/pubmed/25435379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiotec.2014.11.008
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