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A 3D tension bioreactor platform to study the interplay between ECM stiffness and tumor phenotype

Extracellular matrix (ECM) structure, composition, and stiffness have profound effects on tissue development and pathologies such as cardiovascular disease and cancer. Accordingly, a variety of synthetic hydrogel systems have been designed to study the impact of ECM composition, density, mechanics,...

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Detalhes bibliográficos
Publicado no:J Biotechnol
Main Authors: Cassereau, Luke, Miroshnikova, Yekaterina A., Ou, Guanqing, Lakins, Johnathon, Weaver, Valerie M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454500/
https://ncbi.nlm.nih.gov/pubmed/25435379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiotec.2014.11.008
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