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A 3D tension bioreactor platform to study the interplay between ECM stiffness and tumor phenotype

Extracellular matrix (ECM) structure, composition, and stiffness have profound effects on tissue development and pathologies such as cardiovascular disease and cancer. Accordingly, a variety of synthetic hydrogel systems have been designed to study the impact of ECM composition, density, mechanics,...

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Библиографические подробности
Опубликовано в: :J Biotechnol
Главные авторы: Cassereau, Luke, Miroshnikova, Yekaterina A., Ou, Guanqing, Lakins, Johnathon, Weaver, Valerie M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454500/
https://ncbi.nlm.nih.gov/pubmed/25435379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiotec.2014.11.008
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