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Tumor-induced solid stress activates β-catenin signaling to drive malignant behavior in normal, tumor-adjacent cells

Recent work by Fernández-Sánchez and coworkers examining the impact of applied pressure on the malignant phenotype of murine colon tissue in vivo revealed that mechanical perturbations can drive malignant behavior in genetically normal cells. Their findings build upon an existing understanding of ho...

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Detalles Bibliográficos
Publicado en:Bioessays
Main Authors: Ou, Guanqing, Weaver, Valerie Marie
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731088/
https://ncbi.nlm.nih.gov/pubmed/26439949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201500090
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