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DNA-methyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients

The down regulation of glutamic acid decarboxylase67 (GAD1), reelin (RELN), and BDNF expression in brain of schizophrenia (SZ) and bipolar (BP) disorder patients is associated with overexpression of DNA methyltransferase1 (DNMT1) and ten-eleven translocase methylcytosine dioxygenase1 (TET1). DNMT1 a...

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Publicado en:Schizophr Res
Autores principales: Dong, E., Ruzicka, W. B., Grayson, D.R., Guidotti, A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451449/
https://ncbi.nlm.nih.gov/pubmed/25476119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2014.10.030
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