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Factors to preserve CpG-rich sequences in methylated CpG islands

BACKGROUND: Mammalian CpG islands (CGIs) normally escape DNA methylation in all adult tissues and developmental stages. However, in our previous study we unexpectedly identified many methylated CGIs in human peripheral blood leukocytes. Methylated CpG dinucleotides convert to TpG dinucleotides throu...

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Bibliografische gegevens
Gepubliceerd in:BMC Genomics
Hoofdauteurs: Miyahara, Hiroki, Hirose, Osamu, Satou, Kenji, Yamada, Yoichi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417305/
https://ncbi.nlm.nih.gov/pubmed/25879481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1286-x
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