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Factors to preserve CpG-rich sequences in methylated CpG islands

BACKGROUND: Mammalian CpG islands (CGIs) normally escape DNA methylation in all adult tissues and developmental stages. However, in our previous study we unexpectedly identified many methylated CGIs in human peripheral blood leukocytes. Methylated CpG dinucleotides convert to TpG dinucleotides throu...

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Foilsithe in:BMC Genomics
Main Authors: Miyahara, Hiroki, Hirose, Osamu, Satou, Kenji, Yamada, Yoichi
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417305/
https://ncbi.nlm.nih.gov/pubmed/25879481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1286-x
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