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Factors to preserve CpG-rich sequences in methylated CpG islands

BACKGROUND: Mammalian CpG islands (CGIs) normally escape DNA methylation in all adult tissues and developmental stages. However, in our previous study we unexpectedly identified many methylated CGIs in human peripheral blood leukocytes. Methylated CpG dinucleotides convert to TpG dinucleotides throu...

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Bibliografiska uppgifter
I publikationen:BMC Genomics
Huvudupphovsmän: Miyahara, Hiroki, Hirose, Osamu, Satou, Kenji, Yamada, Yoichi
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417305/
https://ncbi.nlm.nih.gov/pubmed/25879481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1286-x
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