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Factors to preserve CpG-rich sequences in methylated CpG islands

BACKGROUND: Mammalian CpG islands (CGIs) normally escape DNA methylation in all adult tissues and developmental stages. However, in our previous study we unexpectedly identified many methylated CGIs in human peripheral blood leukocytes. Methylated CpG dinucleotides convert to TpG dinucleotides throu...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Miyahara, Hiroki, Hirose, Osamu, Satou, Kenji, Yamada, Yoichi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417305/
https://ncbi.nlm.nih.gov/pubmed/25879481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1286-x
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