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In vitro methylation of CpG-rich islands.
CpG islands are distinguishable from the bulk of vertebrate DNA for being unmethylated and CpG-rich. Since CpG doublets are the specific target of eukaryotic DNA methyltransferases, CpG-rich sequences might be expected to be good methyl-accepting substrates in vitro, despite their unmethylated in vi...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1989
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC335126/ https://ncbi.nlm.nih.gov/pubmed/2587255 |
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