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In vitro methylation of CpG-rich islands.

CpG islands are distinguishable from the bulk of vertebrate DNA for being unmethylated and CpG-rich. Since CpG doublets are the specific target of eukaryotic DNA methyltransferases, CpG-rich sequences might be expected to be good methyl-accepting substrates in vitro, despite their unmethylated in vi...

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Sonraí Bibleagrafaíochta
Main Authors: Carotti, D, Palitti, F, Lavia, P, Strom, R
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1989
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC335126/
https://ncbi.nlm.nih.gov/pubmed/2587255
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