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DNA-methyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients

The down regulation of glutamic acid decarboxylase67 (GAD1), reelin (RELN), and BDNF expression in brain of schizophrenia (SZ) and bipolar (BP) disorder patients is associated with overexpression of DNA methyltransferase1 (DNMT1) and ten-eleven translocase methylcytosine dioxygenase1 (TET1). DNMT1 a...

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Détails bibliographiques
Publié dans:Schizophr Res
Auteurs principaux: Dong, E., Ruzicka, W. B., Grayson, D.R., Guidotti, A.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451449/
https://ncbi.nlm.nih.gov/pubmed/25476119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2014.10.030
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