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A novel method to analyze 5-hydroxymethylcytosine in CpG sequences using maintenance DNA methyltransferase, DNMT1

Hydroxymethylcytosine has been shown to be involved in DNA demethylation and gene expression. Although methods to determine the position of hydroxymethylcytosine at single-base resolution have been reported, these methods involve some difficulties. Here, we report a simple method to analyze hydroxym...

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Bibliografske podrobnosti
izdano v:FEBS Open Bio
Main Authors: Takahashi, Saori, Suetake, Isao, Engelhardt, Jan, Tajima, Shoji
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575954/
https://ncbi.nlm.nih.gov/pubmed/26504739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2015.09.003
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