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A novel method to analyze 5-hydroxymethylcytosine in CpG sequences using maintenance DNA methyltransferase, DNMT1

Hydroxymethylcytosine has been shown to be involved in DNA demethylation and gene expression. Although methods to determine the position of hydroxymethylcytosine at single-base resolution have been reported, these methods involve some difficulties. Here, we report a simple method to analyze hydroxym...

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Publicat a:FEBS Open Bio
Autors principals: Takahashi, Saori, Suetake, Isao, Engelhardt, Jan, Tajima, Shoji
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575954/
https://ncbi.nlm.nih.gov/pubmed/26504739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2015.09.003
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