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A novel method to analyze 5-hydroxymethylcytosine in CpG sequences using maintenance DNA methyltransferase, DNMT1

Hydroxymethylcytosine has been shown to be involved in DNA demethylation and gene expression. Although methods to determine the position of hydroxymethylcytosine at single-base resolution have been reported, these methods involve some difficulties. Here, we report a simple method to analyze hydroxym...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Takahashi, Saori, Suetake, Isao, Engelhardt, Jan, Tajima, Shoji
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575954/
https://ncbi.nlm.nih.gov/pubmed/26504739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2015.09.003
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