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Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1)

Methylation of cytosine in DNA plays a crucial role in development through inheritable gene silencing. The DNA methyltransferase Dnmt1 is responsible for the propagation of methylation patterns to the next generation via its preferential methylation of hemimethylated CpG sites in the genome; however...

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Detalles Bibliográficos
Main Authors: Takeshita, Kohei, Suetake, Isao, Yamashita, Eiki, Suga, Michihiro, Narita, Hirotaka, Nakagawa, Atsushi, Tajima, Shoji
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107267/
https://ncbi.nlm.nih.gov/pubmed/21518897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019629108
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