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Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1)

Methylation of cytosine in DNA plays a crucial role in development through inheritable gene silencing. The DNA methyltransferase Dnmt1 is responsible for the propagation of methylation patterns to the next generation via its preferential methylation of hemimethylated CpG sites in the genome; however...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Takeshita, Kohei, Suetake, Isao, Yamashita, Eiki, Suga, Michihiro, Narita, Hirotaka, Nakagawa, Atsushi, Tajima, Shoji
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107267/
https://ncbi.nlm.nih.gov/pubmed/21518897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019629108
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