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Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1)
Methylation of cytosine in DNA plays a crucial role in development through inheritable gene silencing. The DNA methyltransferase Dnmt1 is responsible for the propagation of methylation patterns to the next generation via its preferential methylation of hemimethylated CpG sites in the genome; however...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3107267/ https://ncbi.nlm.nih.gov/pubmed/21518897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019629108 |
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