Epigenetic Protection of Vertebrate Lymphoid Progenitor Cells by Dnmt1

DNA methylation is a universal epigenetic mechanism involved in regulation of gene expression and genome stability. The DNA maintenance methylase DNMT1 ensures that DNA methylation patterns are faithfully transmitted to daughter cells during cell division. Because loss of DNMT1 is lethal, a pan-orga...

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Udgivet i:iScience
Main Authors: Iwanami, Norimasa, Takeshita, Kohei, Lawir, Divine-Fondzenyuy, Suetake, Isao, Tajima, Shoji, Sikora, Katarzyna, Trancoso, Inês, ÓMeara, Connor, Siamishi, Iliana, Takahama, Yousuke, Furutani-Seiki, Makoto, Kondoh, Hisato, Yonezawa, Yasushige, Schorpp, Michael, Boehm, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322073/
https://ncbi.nlm.nih.gov/pubmed/32585597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101260
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