Forward Genetic Screens in Zebrafish Identify Pre-mRNA-Processing Pathways Regulating Early T Cell Development

Lymphocytes represent basic components of vertebrate adaptive immune systems, suggesting the utility of non-mammalian models to define the molecular basis of their development and differentiation. Our forward genetic screens in zebrafish for recessive mutations affecting early T cell development rev...

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Pubblicato in:Cell Rep
Autori principali: Iwanami, Norimasa, Sikora, Katarzyna, Richter, Andreas S., Mönnich, Maren, Guerri, Lucia, Soza-Ried, Cristian, Lawir, Divine-Fondzenyuy, Mateos, Fernando, Hess, Isabell, O’Meara, Connor P., Schorpp, Michael, Boehm, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5149563/
https://ncbi.nlm.nih.gov/pubmed/27880902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.11.003
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