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Transgenerational inheritance of impaired larval T cell development in zebrafish

Evidence for transgenerational inheritance of epigenetic information in vertebrates is scarce. Aberrant patterns of DNA methylation in gametes may set the stage for transmission into future generations. Here, we describe a viable hypomorphic allele of dnmt1 in zebrafish that causes widespread demeth...

詳細記述

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書誌詳細
出版年:Nat Commun
主要な著者: Iwanami, Norimasa, Lawir, Divine-Fondzenyuy, Sikora, Katarzyna, O´Meara, Connor, Takeshita, Kohei, Schorpp, Michael, Boehm, Thomas
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7481223/
https://ncbi.nlm.nih.gov/pubmed/32908148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18289-9
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