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Transgenerational inheritance of impaired larval T cell development in zebrafish
Evidence for transgenerational inheritance of epigenetic information in vertebrates is scarce. Aberrant patterns of DNA methylation in gametes may set the stage for transmission into future generations. Here, we describe a viable hypomorphic allele of dnmt1 in zebrafish that causes widespread demeth...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7481223/ https://ncbi.nlm.nih.gov/pubmed/32908148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18289-9 |
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