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Ontogeny of CpG island methylation and specificity of DNMT3 methyltransferases during embryonic development in the mouse

BACKGROUND: In the mouse, the patterns of DNA methylation are established during early embryonic development in the epiblast. We quantified the targets and kinetics of DNA methylation acquisition in epiblast cells, and determined the contribution of the de novo methyltransferases DNMT3A and DNMT3B t...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Auclair, Ghislain, Guibert, Sylvain, Bender, Ambre, Weber, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295324/
https://ncbi.nlm.nih.gov/pubmed/25476147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0545-5
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