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Ontogeny of CpG island methylation and specificity of DNMT3 methyltransferases during embryonic development in the mouse

BACKGROUND: In the mouse, the patterns of DNA methylation are established during early embryonic development in the epiblast. We quantified the targets and kinetics of DNA methylation acquisition in epiblast cells, and determined the contribution of the de novo methyltransferases DNMT3A and DNMT3B t...

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Bibliografski detalji
Izdano u:Genome Biol
Glavni autori: Auclair, Ghislain, Guibert, Sylvain, Bender, Ambre, Weber, Michael
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295324/
https://ncbi.nlm.nih.gov/pubmed/25476147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0545-5
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