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Ontogeny of CpG island methylation and specificity of DNMT3 methyltransferases during embryonic development in the mouse

BACKGROUND: In the mouse, the patterns of DNA methylation are established during early embryonic development in the epiblast. We quantified the targets and kinetics of DNA methylation acquisition in epiblast cells, and determined the contribution of the de novo methyltransferases DNMT3A and DNMT3B t...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Genome Biol
Päätekijät: Auclair, Ghislain, Guibert, Sylvain, Bender, Ambre, Weber, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295324/
https://ncbi.nlm.nih.gov/pubmed/25476147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0545-5
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