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DNA-methyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients

The down regulation of glutamic acid decarboxylase67 (GAD1), reelin (RELN), and BDNF expression in brain of schizophrenia (SZ) and bipolar (BP) disorder patients is associated with overexpression of DNA methyltransferase1 (DNMT1) and ten-eleven translocase methylcytosine dioxygenase1 (TET1). DNMT1 a...

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Detalhes bibliográficos
Publicado no:Schizophr Res
Main Authors: Dong, E., Ruzicka, W. B., Grayson, D.R., Guidotti, A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451449/
https://ncbi.nlm.nih.gov/pubmed/25476119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2014.10.030
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