Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy

The PTEN-induced putative kinase protein 1 (PINK1) and ubiquitin (UB) ligase PARKIN direct damaged mitochondria for mitophagy. PINK1 promotes PARKIN recruitment to the mitochondrial outer membrane (MOM) for ubiquitylation of MOM proteins with canonical and noncanonical UB chains. PINK1 phosphorylate...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Ordureau, Alban, Heo, Jin-Mi, Duda, David M., Paulo, Joao A., Olszewski, Jennifer L., Yanishevski, David, Rinehart, Jesse, Schulman, Brenda A., Harper, J. Wade
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450373/
https://ncbi.nlm.nih.gov/pubmed/25969509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1506593112
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker