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Effects of Age and Sex on the Single-Dose Pharmacokinetics and Pharmacodynamics of Apixaban
BACKGROUND AND OBJECTIVES: The effects of age and sex on apixaban pharmacokinetics and pharmacodynamics were studied. METHODS: This was an open-label, single-dose, 2 × 2 factorial study. Healthy young (aged 18–40 years) and elderly (aged ≥65 years) male and female subjects received a single oral 20 ...
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| 出版年: | Clin Pharmacokinet |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer International Publishing
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4449375/ https://ncbi.nlm.nih.gov/pubmed/25573421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-014-0228-0 |
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