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Effects of Age and Sex on the Single-Dose Pharmacokinetics and Pharmacodynamics of Apixaban

BACKGROUND AND OBJECTIVES: The effects of age and sex on apixaban pharmacokinetics and pharmacodynamics were studied. METHODS: This was an open-label, single-dose, 2 × 2 factorial study. Healthy young (aged 18–40 years) and elderly (aged ≥65 years) male and female subjects received a single oral 20 ...

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Bibliografische gegevens
Gepubliceerd in:Clin Pharmacokinet
Hoofdauteurs: Frost, Charles E., Song, Yan, Shenker, Andrew, Wang, Jessie, Barrett, Yu Chen, Schuster, Alan, Harris, Stuart I., LaCreta, Frank
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer International Publishing 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449375/
https://ncbi.nlm.nih.gov/pubmed/25573421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-014-0228-0
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