Evaluation of the single-dose pharmacokinetics and pharmacodynamics of apixaban in healthy Japanese and Caucasian subjects

PURPOSE: This double-blind, placebo-controlled, intra-subject, dose-escalation study assessed single-dose safety, pharmacokinetics, and pharmacodynamics of apixaban in healthy Japanese and Caucasian subjects. SUBJECTS AND METHODS: Sixteen healthy male Japanese and sixteen healthy male Caucasian subj...

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Publicat a:Clin Pharmacol
Autors principals: Frost, Charles, Shenker, Andrew, Jhee, Stanford, Yu, Zhigang, Wang, Jessie, Bragat, Alexander, Pursley, Janice, LaCreta, Frank
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2018
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207247/
https://ncbi.nlm.nih.gov/pubmed/30498375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S169505
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