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The effect of apixaban on the pharmacokinetics of digoxin and atenolol in healthy subjects

PURPOSE: Apixaban is often coadministered with treatments for cardiovascular comorbidities, which may lead to unintended drug–drug interactions (DDIs). The effects of apixaban on pharmacokinetics (PK) of multidose Lanoxin(®) (digoxin) and single-dose Tenormin(®) (atenolol) and the effects of single-...

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Publicado en:Clin Pharmacol
Autores principales: Frost, Charles, Song, Yan, Yu, Zhigang, Wang, Jessie, Lee, Lois S, Schuster, Alan, Pollack, Allyson, LaCreta, Frank
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327911/
https://ncbi.nlm.nih.gov/pubmed/28260951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S115687
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