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Single- and multiple-dose pharmacokinetics, pharmacodynamics, and safety of apixaban in healthy Chinese subjects

BACKGROUND: The pharmacokinetics (PK), pharmacodynamics (PD), and safety of apixaban were assessed in healthy Chinese subjects in this randomized, placebo-controlled, double-blind, single-sequence, single- and multiple-dose study. SUBJECTS AND METHODS: Eighteen subjects 18–45 years of age were rando...

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Detalhes bibliográficos
Main Authors: Cui, Yimin, Song, Yan, Wang, Jessie, Yu, Zhigang, Schuster, Alan, Barrett, Yu Chen, Frost, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861362/
https://ncbi.nlm.nih.gov/pubmed/24353445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S51981
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