Φορτώνει......

Physical characterization and in vitro biological impact of highly aggregated antibodies separated into size-enriched populations by fluorescence-activated cell sorting

An IgG2 monoclonal antibody (mAb) solution was subjected to stirring, generating high concentrations of nanometer and subvisible particles, which were then successfully size enriched into different size bins by low speed centrifugation or a combination of gravitational sedimentation and Fluorescence...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Pharm Sci
Κύριοι συγγραφείς: Telikepalli, Srivalli, Shinogle, Heather E., Thapa, Prem S., Kim, Jae Hyun, Deshpande, Meghana, Jawa, Vibha, Middaugh, C. Russell, Narhi, Linda O., Joubert, Marisa K., Volkin, David B.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2015
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448733/
https://ncbi.nlm.nih.gov/pubmed/25753756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.24379
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