Structural and functional characterization of a specific antidote for ticagrelor

Ticagrelor is a direct-acting reversibly binding P2Y(12) antagonist and is widely used as an antiplatelet therapy for the prevention of cardiovascular events in acute coronary syndrome patients. However, antiplatelet therapy can be associated with an increased risk of bleeding. Here, we present data...

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Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Buchanan, Andrew, Newton, Philip, Pehrsson, Susanne, Inghardt, Tord, Antonsson, Thomas, Svensson, Peder, Sjögren, Tove, Öster, Linda, Janefeldt, Annika, Sandinge, Ann-Sofie, Keyes, Feenagh, Austin, Mark, Spooner, Jennifer, Gennemark, Peter, Penney, Mark, Howells, Garnet, Vaughan, Tristan, Nylander, Sven
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2015
Soggetti:
Thrombosis and Hemostasis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447862/
https://ncbi.nlm.nih.gov/pubmed/25788700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-01-622928
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