Structural and functional characterization of a specific antidote for ticagrelor

Ticagrelor is a direct-acting reversibly binding P2Y(12) antagonist and is widely used as an antiplatelet therapy for the prevention of cardiovascular events in acute coronary syndrome patients. However, antiplatelet therapy can be associated with an increased risk of bleeding. Here, we present data...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Buchanan, Andrew, Newton, Philip, Pehrsson, Susanne, Inghardt, Tord, Antonsson, Thomas, Svensson, Peder, Sjögren, Tove, Öster, Linda, Janefeldt, Annika, Sandinge, Ann-Sofie, Keyes, Feenagh, Austin, Mark, Spooner, Jennifer, Gennemark, Peter, Penney, Mark, Howells, Garnet, Vaughan, Tristan, Nylander, Sven
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447862/
https://ncbi.nlm.nih.gov/pubmed/25788700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-01-622928
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