Structural and functional characterization of a specific antidote for ticagrelor

Ticagrelor is a direct-acting reversibly binding P2Y(12) antagonist and is widely used as an antiplatelet therapy for the prevention of cardiovascular events in acute coronary syndrome patients. However, antiplatelet therapy can be associated with an increased risk of bleeding. Here, we present data...

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Publicado en:Blood
Autores principales: Buchanan, Andrew, Newton, Philip, Pehrsson, Susanne, Inghardt, Tord, Antonsson, Thomas, Svensson, Peder, Sjögren, Tove, Öster, Linda, Janefeldt, Annika, Sandinge, Ann-Sofie, Keyes, Feenagh, Austin, Mark, Spooner, Jennifer, Gennemark, Peter, Penney, Mark, Howells, Garnet, Vaughan, Tristan, Nylander, Sven
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2015
Materias:
Thrombosis and Hemostasis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447862/
https://ncbi.nlm.nih.gov/pubmed/25788700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-01-622928
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