Structural and functional characterization of a specific antidote for ticagrelor

Ticagrelor is a direct-acting reversibly binding P2Y(12) antagonist and is widely used as an antiplatelet therapy for the prevention of cardiovascular events in acute coronary syndrome patients. However, antiplatelet therapy can be associated with an increased risk of bleeding. Here, we present data...

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Publicat a:Blood
Autors principals: Buchanan, Andrew, Newton, Philip, Pehrsson, Susanne, Inghardt, Tord, Antonsson, Thomas, Svensson, Peder, Sjögren, Tove, Öster, Linda, Janefeldt, Annika, Sandinge, Ann-Sofie, Keyes, Feenagh, Austin, Mark, Spooner, Jennifer, Gennemark, Peter, Penney, Mark, Howells, Garnet, Vaughan, Tristan, Nylander, Sven
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2015
Matèries:
Thrombosis and Hemostasis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447862/
https://ncbi.nlm.nih.gov/pubmed/25788700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-01-622928
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