Therapeutic effects of cell-permeant peptides that activate G proteins downstream of growth factors

In eukaryotes, receptor tyrosine kinases (RTKs) and trimeric G proteins are two major signaling hubs. Signal transduction via trimeric G proteins has long been believed to be triggered exclusively by G protein-coupled receptors (GPCRs). This paradigm has recently been challenged by several studies o...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Ma, Gary S., Aznar, Nicolas, Kalogriopoulos, Nicholas, Midde, Krishna K., Lopez-Sanchez, Inmaculada, Sato, Emi, Dunkel, Ying, Gallo, Richard L., Ghosh, Pradipta
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2015
Предметы:
PNAS Plus
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443320/
https://ncbi.nlm.nih.gov/pubmed/25926659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505543112
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