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Focal adhesions are foci for tyrosine-based signal transduction via GIV/Girdin and G proteins
GIV/Girdin is a multimodular signal transducer and a bona fide metastasis-related protein. As a guanidine exchange factor (GEF), GIV modulates signals initiated by growth factors (chemical signals) by activating the G protein Gαi. Here we report that mechanical signals triggered by the extracellular...
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| Veröffentlicht in: | Mol Biol Cell |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Cell Biology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4666128/ https://ncbi.nlm.nih.gov/pubmed/26446841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-07-0496 |
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