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GIV/Girdin binds Exocyst subunit-Exo70 and Regulates Exocytosis of GLUT4 Storage Vesicles

Insulin resistance (IR) is a metabolic disorder characterized by impaired glucose uptake in response to insulin. The current paradigm for insulin signaling centers upon the insulin receptor (InsR) and its substrate IRS1; the latter is believed to be the chief conduit for post-receptor signaling. We...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Lopez-Sanchez, Inmaculada, Ma, Gary S., Pedram, Shabnam, Kalogriopoulos, Nicholas, Ghosh, Pradipta
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659757/
https://ncbi.nlm.nih.gov/pubmed/26514725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.10.111
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