Endosidin2 targets conserved exocyst complex subunit EXO70 to inhibit exocytosis

The exocyst complex regulates the last steps of exocytosis, which is essential to organisms across kingdoms. In humans, its dysfunction is correlated with several significant diseases, such as diabetes and cancer progression. Investigation of the dynamic regulation of the evolutionarily conserved ex...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Zhang, Chunhua, Brown, Michelle Q., van de Ven, Wilhelmina, Zhang, Zhi-Min, Wu, Bin, Young, Michael C., Synek, Lukáš, Borchardt, Dan, Harrison, Reed, Pan, Songqin, Luo, Nan, Huang, Yu-ming M., Ghang, Yoo-Jin, Ung, Nolan, Li, Ruixi, Isley, Jonathan, Morikis, Dimitrios, Song, Jikui, Guo, Wei, Hooley, Richard J., Chang, Chia-en A., Yang, Zhenbiao, Zarsky, Viktor, Muday, Gloria K., Hicks, Glenn R., Raikhel, Natasha V.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711834/
https://ncbi.nlm.nih.gov/pubmed/26607451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521248112
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