Endosidin2 targets conserved exocyst complex subunit EXO70 to inhibit exocytosis

The exocyst complex regulates the last steps of exocytosis, which is essential to organisms across kingdoms. In humans, its dysfunction is correlated with several significant diseases, such as diabetes and cancer progression. Investigation of the dynamic regulation of the evolutionarily conserved ex...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Zhang, Chunhua, Brown, Michelle Q., van de Ven, Wilhelmina, Zhang, Zhi-Min, Wu, Bin, Young, Michael C., Synek, Lukáš, Borchardt, Dan, Harrison, Reed, Pan, Songqin, Luo, Nan, Huang, Yu-ming M., Ghang, Yoo-Jin, Ung, Nolan, Li, Ruixi, Isley, Jonathan, Morikis, Dimitrios, Song, Jikui, Guo, Wei, Hooley, Richard J., Chang, Chia-en A., Yang, Zhenbiao, Zarsky, Viktor, Muday, Gloria K., Hicks, Glenn R., Raikhel, Natasha V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711834/
https://ncbi.nlm.nih.gov/pubmed/26607451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521248112
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