Focal adhesions are foci for tyrosine-based signal transduction via GIV/Girdin and G proteins

GIV/Girdin is a multimodular signal transducer and a bona fide metastasis-related protein. As a guanidine exchange factor (GEF), GIV modulates signals initiated by growth factors (chemical signals) by activating the G protein Gαi. Here we report that mechanical signals triggered by the extracellular...

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Dettagli Bibliografici
Pubblicato in:Mol Biol Cell
Autori principali: Lopez-Sanchez, Inmaculada, Kalogriopoulos, Nicholas, Lo, I-Chung, Kabir, Firooz, Midde, Krishna K., Wang, Honghui, Ghosh, Pradipta
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2015
Soggetti:
Brief Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666128/
https://ncbi.nlm.nih.gov/pubmed/26446841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-07-0496
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