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Heterotrimeric G Proteins: Breaking the rules of engagement, space and time

Canonical signal transduction via heterotrimeric G proteins is spatially and temporally restricted, i.e., triggered exclusively at the plasma membrane (PM), only by agonist activation of G-protein-coupled receptors (GPCRs) via a process that completes within a few hundred milliseconds. Recently, a r...

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Detalhes bibliográficos
Publicado no:Bioessays
Main Authors: Midde, Krishna K., Aznar, Nicolas, Kalogriopoulos, Nicholas, Ghosh, Pradipta
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123561/
https://ncbi.nlm.nih.gov/pubmed/26879989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201500133
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