GIV/Girdin activates Gαi and inhibits Gαs via the same motif

We previously showed that guanine nucleotide-binding (G) protein α subunit (Gα)-interacting vesicle-associated protein (GIV), a guanine-nucleotide exchange factor (GEF), transactivates Gα activity-inhibiting polypeptide 1 (Gαi) proteins in response to growth factors, such as EGF, using a short C-ter...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gupta, Vijay, Bhandari, Deepali, Leyme, Anthony, Aznar, Nicolas, Midde, Krishna K., Lo, I-Chung, Ear, Jason, Niesman, Ingrid, López-Sánchez, Inmaculada, Blanco-Canosa, Juan Bautista, von Zastrow, Mark, Garcia-Marcos, Mikel, Farquhar, Marilyn G., Ghosh, Pradipta
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047194/
https://ncbi.nlm.nih.gov/pubmed/27621449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609502113
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