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An Important Role of CDK Inhibitor p18(INK4c) in Modulating Antigen Receptor-Mediated T Cell Proliferation
The inhibitors of cyclin-dependent kinase (CDK) 4 (INK4) bind CDK4/6 to prevent their association with D-cyclins and G(1) cell cycle initiation and progression. We report here that among the seven CDK inhibitors, p18(INK4c) played an important role in modulating TCR-mediated T cell proliferation. Lo...
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| Опубликовано в: : | J Immunol |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4435948/ https://ncbi.nlm.nih.gov/pubmed/11544316 |
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